Levocetirizine Hydrochloride , Acelofenac Paracetamol

 Allergy is an immune response to those substances that are usually not harmful. Such substances are called allergens. The immune system is oversensitive in people with certain allergy. When our body comes into contact with certain allergens such as pollens, ragweed, pet dander, or dust particles; it starts releasing chemicals called histamines.

These chemicals trigger the allergy symptoms that include watery eyes, runny nose, itching eyes/nose, sneezing, hives, and itching. Under such conditions, doctors prescribe us antihistamines which can reduce or block the histamines and hence stop allergy symptoms. Antihistamines cause blood vessels to expand and the skin to swell, which may help in protecting the body.

Antihistamines can be categorized in three types-

First generation - The first generation H1-antihistamines penetrate easily into the brain to cause sedation, drowsiness, fatigue and impaired concentration and memory causing detrimental effects on learning and examination performance in children and on impairment of the ability of adults to work and drive.

Second generation - Second-generation histamine H1 receptor antagonists (antihistamines) have been developed to reduce or eliminate the sedation and anticholinergic adverse effects that occur with older H1 receptor antagonists.

Third generation - is less anaesthetizing/sedating antihistamine and has emerged for the treatment of allergic rhinitis and chronic urticaria.

Levocetirizine hydrochloride is a second generation, non-sedative, antihistamine that reduces the effects of natural chemical histamine in the body. As histamine plays an important role in angiogenesis during an allergic inflammatory reaction, attempt to block the action of histamine may modulate the expression of proangiogenic factors and thus may prevent angiogenesis. Amster Labs has received several acknowledgments for the production of Levocetirizine hydrochloride which they develop in order to provide protection from various allergic conditions.

 

Inflammation is another important part of our immune response against certain injuries or infections. When our cells get damaged somehow, our body starts releasing antibodies and proteins along with an increased blood flow to the damaged area. This all is referred to as inflammation and the signs of acute inflammation include redness, swelling, heat and sometimes pain and loss of function. Aceclofenac Paracetamol Tablet prepared at Amster Labs contains Aceclofenac and Paracetamol as its active ingredients. These ingredients work in the superlative way of reducing the pain and inflammation in the suffering person.

 

Aceclofenac Paracetamol tablet manufactured at Amster Labs is preferred for the treatment of Cold, Ear pain, Fever, Flu, headache, Joint pain etc. This product has also been known to protect the body from various symptoms such as: stiffness and swelling of joints associated with Rheumatoid arthritis, Painful and tender joints associated with Osteoarthritis and Pain and stiffness associated with spondylitis. Aceclofenac Paracetamol blocks the consequences of cyclo-oxygenase (COX) enzymes which are always present in a standard amount in the body. In case of certain injury these COX enzymes assist in producing prostaglandins which reflect the symptoms of inflammation i.e., redness, swelling, and pain at the place of wound or damage. Inhibition of COX enzyme using Aceclofenac Paracetamol helps in minimizing the production of prostaglandins and thereafter helps in reducing the pain and inflammation at the site of injury.